Lynch Syndrome Module for GPs 1

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1. What is your name? *

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2. What is your job title? *

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3. In which GP surgery and Trust do you work? *

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4. What is your email address? *

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5. Why are you undertaking this training? *

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6. Approximately, how many colorectal and endometrial cancers are caused Lynch syndrome? *

1%
3%
5%
10%

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7. Lynch syndrome predisposes to a variety of cancer types. Typically: *

Colorectal, endometrial, liver, lung and breast cancers
Colorectal, endometrial, breast and bone cancers
Colorectal and endometrial cancer only
Colorectal, endometrial, ovarian, urinary tract, gastric, small intestine, hepato-biliary, sebaceous and CNS cancers

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8. The cancer risk in Lynch syndrome can be managed by: *

Regular colonoscopy with polypectomy
Surgery
Lifestyle recomendations
Aspirin
One-off screening for H. Pylori
All of the above

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9. What is the inheritance pattern in Lynch syndrome? *

Autosomal dominant: Offspring have a 25% risk of having the same condition
Autosomal dominant: Offspring have a 50% chance of having the same condition
Autosomal recesive: Offspring have a 25% chance of having the same condition
Autosomal recesive: Offspring have a 50% chance of having the same condition

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10. What is the impact of understanding that the cancer has been caused by an inherited cancer syndrome for the patient? *

A predictive biomarker of treatment response and/or prognosis
An explanation for why cancer occurred
Information about secondary cancer risk and prevention
All of the above

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11. What is the impact of understanding that the cancer has been caused by an inherited cancer syndrome, for the patient's family members? *

Permit the implementation of cancer screening and risk-reducing interventions
Inform future cancer risk
Aid reproductive decisions (e.g. pre-implantation genetic diagnosis)
All of the above

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